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Conditional corticotropin-releasing hormone overexpression in the mouse forebrain enhances rapid eye movement sleep

Impaired sleep and enhanced stress hormone secretion are the hallmarks of stress-related disorders, including major depression. The central neuropeptide, corticotropin-releasing hormone (CRH), is a key hormone that regulates humoral and behavioral adaptation to stress. Its prolonged hypersecretion i...

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Detalles Bibliográficos
Autores principales: Kimura, M, Müller-Preuss, P, Lu, A, Wiesner, E, Flachskamm, C, Wurst, W, Holsboer, F, Deussing, J M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834335/
https://www.ncbi.nlm.nih.gov/pubmed/19455148
http://dx.doi.org/10.1038/mp.2009.46