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A role for elongator in zygotic paternal genome demethylation

The life cycle of mammals begins when a sperm enters an egg. Immediately after fertilization, both the maternal and paternal genomes undergo dramatic reprogramming to prepare for the transition from germ cell to somatic cell transcription programs 1. One of the molecular events that takes place duri...

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Detalles Bibliográficos
Autores principales: Okada, Yuki, Yamagata, Kazuo, Hong, Kwonho, Wakayama, Teruhiko, Zhang, Yi
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834414/
https://www.ncbi.nlm.nih.gov/pubmed/20054296
http://dx.doi.org/10.1038/nature08732