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HIV-1 V3 envelope deep sequencing for clinical plasma specimens failing in phenotypic tropism assays

BACKGROUND: HIV-1 infected patients for whom standard gp160 phenotypic tropism testing failed are currently excluded from co-receptor antagonist treatment. To provide patients with maximal treatment options, massively parallel sequencing of the envelope V3 domain, in combination with tropism predict...

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Detalles Bibliográficos
Autores principales: Vandenbroucke, Ina, Van Marck, Herwig, Mostmans, Wendy, Van Eygen, Veerle, Rondelez, Evelien, Thys, Kim, Van Baelen, Kurt, Fransen, Katrien, Vaira, Dolores, Kabeya, Kabamba, De Wit, Stephane, Florence, Eric, Moutschen, Michel, Vandekerckhove, Linos, Verhofstede, Chris, Stuyver, Lieven J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834596/
https://www.ncbi.nlm.nih.gov/pubmed/20804564
http://dx.doi.org/10.1186/1742-6405-7-4