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Periplasmic expression of soluble single chain T cell receptors is rescued by the chaperone FkpA

BACKGROUND: Efficient expression systems exist for antibody (Ab) molecules, which allow for characterization of large numbers of individual Ab variants. In contrast, such expression systems have been lacking for soluble T cell receptors (TCRs). Attempts to generate bacterial systems have generally r...

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Detalles Bibliográficos
Autores principales: Gunnarsen, Kristin S, Lunde, Elin, Kristiansen, Per E, Bogen, Bjarne, Sandlie, Inger, Løset, Geir Å
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834602/
https://www.ncbi.nlm.nih.gov/pubmed/20128915
http://dx.doi.org/10.1186/1472-6750-10-8