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Periplasmic expression of soluble single chain T cell receptors is rescued by the chaperone FkpA
BACKGROUND: Efficient expression systems exist for antibody (Ab) molecules, which allow for characterization of large numbers of individual Ab variants. In contrast, such expression systems have been lacking for soluble T cell receptors (TCRs). Attempts to generate bacterial systems have generally r...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834602/ https://www.ncbi.nlm.nih.gov/pubmed/20128915 http://dx.doi.org/10.1186/1472-6750-10-8 |