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In situ detection of Gag-specific CD8(+ )cells in the GI tract of SIV infected Rhesus macaques

BACKGROUND: SIV and HIV predominantly replicate in lymphoid tissue, but the study of virus specific CD8(+ )T cells in intact lymphoid tissue is difficult, as traditional in situ tetramer staining requires fresh tissue. RESULTS: In this report, we demonstrate a novel technique using Qdot 655-conjugat...

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Detalles Bibliográficos
Autores principales: Tjernlund, Annelie, Zhu, Jia, Laing, Kerry, Diem, Kurt, McDonald, David, Vazquez, Julio, Cao, Jianhong, Ohlen, Claes, McElrath, M Juliana, Picker, Louis J, Corey, Lawrence
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834607/
https://www.ncbi.nlm.nih.gov/pubmed/20158906
http://dx.doi.org/10.1186/1742-4690-7-12