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The role of glucocorticoid receptor phosphorylation in Mcl-1 and NOXA gene expression

BACKGROUND: The cyclin-dependent kinase (CDK) and mitogen-activated protein kinase (MAPK) mediated phosphorylation of glucocorticoid receptor (GR) exerts opposite effects on GR transcriptional activity and affects other posttranslational modifications within this protein. The major phosphorylation s...

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Detalles Bibliográficos
Autores principales: Lynch, James T, Rajendran, Ramkumar, Xenaki, Georgia, Berrou, Ilhem, Demonacos, Constantinos, Krstic-Demonacos, Marija
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834612/
https://www.ncbi.nlm.nih.gov/pubmed/20156337
http://dx.doi.org/10.1186/1476-4598-9-38