Small RNA interference-mediated gene silencing of heparanase abolishes the invasion, metastasis and angiogenesis of gastric cancer cells

BACKGROUND: Heparanase facilitates the invasion and metastasis of cancer cells, and is over-expressed in many kinds of malignancies. Our studies indicated that heparanase was frequently expressed in advanced gastric cancers. The aim of this study is to determine whether silencing of heparanase expre...

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Detalles Bibliográficos
Autores principales: Zheng, Liduan, Jiang, Guosong, Mei, Hong, Pu, Jiarui, Dong, Jihua, Hou, Xiaohua, Tong, Qiangsong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834619/
https://www.ncbi.nlm.nih.gov/pubmed/20137078
http://dx.doi.org/10.1186/1471-2407-10-33

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834619/
https://www.ncbi.nlm.nih.gov/pubmed/20137078
http://dx.doi.org/10.1186/1471-2407-10-33

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