Comparison of three rapamycin dosing schedules in A/J Tsc2(+/- )mice and improved survival with angiogenesis inhibitor or asparaginase treatment in mice with subcutaneous tuberous sclerosis related tumors

BACKGROUND: Tuberous Sclerosis Complex (TSC) is an autosomal dominant tumor disorder characterized by the growth of hamartomas in various organs including the kidney, brain, skin, lungs, and heart. Rapamycin has been shown to reduce the size of kidney angiomyolipomas associated with TSC; however, tu...

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Detalles Bibliográficos
Autores principales: Woodrum, Chelsey, Nobil, Alison, Dabora, Sandra L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834646/
https://www.ncbi.nlm.nih.gov/pubmed/20146790
http://dx.doi.org/10.1186/1479-5876-8-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834646/
https://www.ncbi.nlm.nih.gov/pubmed/20146790
http://dx.doi.org/10.1186/1479-5876-8-14

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