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NAD(+ )metabolite levels as a function of vitamins and calorie restriction: evidence for different mechanisms of longevity

BACKGROUND: NAD(+ )is a coenzyme for hydride transfer enzymes and a substrate for sirtuins and other NAD(+)-dependent ADPribose transfer enzymes. In wild-type Saccharomyces cerevisiae, calorie restriction accomplished by glucose limitation extends replicative lifespan in a manner that depends on Sir...

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Detalles Bibliográficos
Autores principales: Evans, Charles, Bogan, Katrina L, Song, Peng, Burant, Charles F, Kennedy, Robert T, Brenner, Charles
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834649/
https://www.ncbi.nlm.nih.gov/pubmed/20175898
http://dx.doi.org/10.1186/1472-6769-10-2