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NAD(+ )metabolite levels as a function of vitamins and calorie restriction: evidence for different mechanisms of longevity
BACKGROUND: NAD(+ )is a coenzyme for hydride transfer enzymes and a substrate for sirtuins and other NAD(+)-dependent ADPribose transfer enzymes. In wild-type Saccharomyces cerevisiae, calorie restriction accomplished by glucose limitation extends replicative lifespan in a manner that depends on Sir...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834649/ https://www.ncbi.nlm.nih.gov/pubmed/20175898 http://dx.doi.org/10.1186/1472-6769-10-2 |