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Insertional mutagenesis enables cleistothecial formation in a non-mating strain of Histoplasma capsulatum

BACKGROUND: Histoplasma capsulatum is a pathogenic ascomycete fungus that rapidly loses mating ability in culture. Loss of mating ability, as well as the organism's low rate of targeted gene replacement, limits techniques available for genetic studies in H. capsulatum. Understanding molecular m...

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Detalles Bibliográficos
Autores principales: Laskowski, Meggan C, Smulian, Alan G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834667/
https://www.ncbi.nlm.nih.gov/pubmed/20158914
http://dx.doi.org/10.1186/1471-2180-10-49