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Lineage-specific co-evolution of the Egf receptor/ligand signaling system
BACKGROUND: The epidermal growth factor receptor (Egfr) with its numerous ligands has fundamental roles in development, cell differentiation and physiology. Dysfunction of the receptor-ligand system contributes to many human malignancies. Consistent with such various tasks, the Egfr gene family has...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834686/ https://www.ncbi.nlm.nih.gov/pubmed/20105326 http://dx.doi.org/10.1186/1471-2148-10-27 |