A GIP Receptor Agonist Exhibits β-Cell Anti-Apoptotic Actions in Rat Models of Diabetes Resulting in Improved β-Cell Function and Glycemic Control

AIMS: The gastrointestinal hormone GIP promotes pancreatic islet function and exerts pro-survival actions on cultured β-cells. However, GIP also promotes lipogenesis, thus potentially restricting its therapeutic use. The current studies evaluated the effects of a truncated GIP analog, D-Ala(2)-GIP(1...

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Detalles Bibliográficos
Autores principales: Widenmaier, Scott B., Kim, Su-Jin, Yang, Gary K., De Los Reyes, Thomas, Nian, Cuilan, Asadi, Ali, Seino, Yutaka, Kieffer, Timothy J., Kwok, Yin Nam, McIntosh, Christopher H. S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834736/
https://www.ncbi.nlm.nih.gov/pubmed/20231880
http://dx.doi.org/10.1371/journal.pone.0009590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834736/
https://www.ncbi.nlm.nih.gov/pubmed/20231880
http://dx.doi.org/10.1371/journal.pone.0009590

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