Early Embryonic Chromosome Instability Results in Stable Mosaic Pattern in Human Tissues

The discovery of copy number variations (CNV) in the human genome opened new perspectives on the study of the genetic causes of inherited disorders and the aetiology of common diseases. Here, a single-cell-level investigation of CNV in different human tissues led us to uncover the phenomenon of mito...

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Detalles Bibliográficos
Autores principales: Mkrtchyan, Hasmik, Gross, Madeleine, Hinreiner, Sophie, Polytiko, Anna, Manvelyan, Marina, Mrasek, Kristin, Kosyakova, Nadezda, Ewers, Elisabeth, Nelle, Heike, Liehr, Thomas, Volleth, Marianne, Weise, Anja
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834743/
https://www.ncbi.nlm.nih.gov/pubmed/20231887
http://dx.doi.org/10.1371/journal.pone.0009591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834743/
https://www.ncbi.nlm.nih.gov/pubmed/20231887
http://dx.doi.org/10.1371/journal.pone.0009591

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