Upregulation of SOCS-3 and PIAS-3 Impairs IL-12-Mediated Interferon-Gamma Response in CD56(+) T Cells in HCV-Infected Heroin Users

BACKGROUND: CD56(+) T cells are abundant in liver and play an important role in host innate immunity against viral infections, including hepatitis C virus (HCV) infection, a common infection among heroin abusers. We thus investigated the in vivo impact of heroin use or heroin use plus HCV infection...

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Detalles Bibliográficos
Autores principales: Ye, Li, Wang, Xu, Metzger, David S., Riedel, Eric, Montaner, Luis J., Ho, Wenzhe
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834757/
https://www.ncbi.nlm.nih.gov/pubmed/20231901
http://dx.doi.org/10.1371/journal.pone.0009602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834757/
https://www.ncbi.nlm.nih.gov/pubmed/20231901
http://dx.doi.org/10.1371/journal.pone.0009602

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