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Impact of Genetic Background on Allele Selection in a Highly Mutable Candida albicans Gene, PNG2

In many microbes rapid mutation of highly mutable contingency genes continually replenishes a pool of variant alleles from which the most suitable are selected, assisting in rapid adaptation and evasion of the immune response. In some contingency genes mutability is achieved through DNA repeats with...

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Detalles Bibliográficos
Autores principales: Zhang, Ningxin, Cannon, Richard D., Holland, Barbara R., Patchett, Mark L., Schmid, Jan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834760/
https://www.ncbi.nlm.nih.gov/pubmed/20231904
http://dx.doi.org/10.1371/journal.pone.0009614