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Combinatorial RNAi Against HIV-1 Using Extended Short Hairpin RNAs

RNA interference (RNAi) is a widely used gene suppression tool that holds great promise as a novel antiviral approach. However, for error-prone viruses including human immunodeficiency virus type 1(HIV-1), a combinatorial approach against multiple conserved sequences is required to prevent the emerg...

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Detalles Bibliográficos
Autores principales: Liu, Ying Poi, von Eije, Karin Jasmijn, Schopman, Nick CT, Westerink, Jan-Tinus, Brake, Olivier ter, Haasnoot, Joost, Berkhout, Ben
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835024/
https://www.ncbi.nlm.nih.gov/pubmed/19672247
http://dx.doi.org/10.1038/mt.2009.176