Cargando…

Combinatorial RNAi Against HIV-1 Using Extended Short Hairpin RNAs

RNA interference (RNAi) is a widely used gene suppression tool that holds great promise as a novel antiviral approach. However, for error-prone viruses including human immunodeficiency virus type 1(HIV-1), a combinatorial approach against multiple conserved sequences is required to prevent the emerg...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Ying Poi, von Eije, Karin Jasmijn, Schopman, Nick CT, Westerink, Jan-Tinus, Brake, Olivier ter, Haasnoot, Joost, Berkhout, Ben
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2009
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835024/ https://www.ncbi.nlm.nih.gov/pubmed/19672247 http://dx.doi.org/10.1038/mt.2009.176

Ejemplares similares

Design of extended short hairpin RNAs for HIV-1 inhibition
por: Liu, Ying Poi, et al.
Publicado: (2007)

Dicer-independent processing of short hairpin RNAs
por: Liu, Ying Poi, et al.
Publicado: (2013)

Anticipating and blocking HIV-1 escape by second generation antiviral shRNAs
por: Schopman, Nick CT, et al.
Publicado: (2010)

Lentiviral Vector Design for Multiple shRNA Expression and Durable HIV-1 Inhibition
por: Brake, Olivier ter, et al.
Publicado: (2008)

Inhibition of HIV-1 by multiple siRNAs expressed from a single microRNA polycistron
por: Liu, Ying Poi, et al.
Publicado: (2008)

Deep sequencing of virus-infected cells reveals HIV-encoded small RNAs
por: Schopman, Nick C.T., et al.
Publicado: (2012)

Trans-inhibition of HIV-1 by a long hairpin RNA expressed within the viral genome
por: Konstantinova, Pavlina, et al.
Publicado: (2007)

RNAi and Cellular miRNAs in Infections by Mammalian Viruses
por: Haasnoot, Joost, et al.
Publicado: (2010)

RNAi-mediated inhibition of HIV-1 by targeting partially complementary viral sequences
por: Liu, Ying Poi, et al.
Publicado: (2009)

Inhibition of human immunodeficiency virus type 1 by RNA interference using long-hairpin RNA
por: Konstantinova, P, et al.
Publicado: (2006)

ESF-EMBO Symposium: Antiviral Applications of RNA Interference
por: ter Brake, Olivier, et al.
Publicado: (2008)

Preclinical test of a lentivirus-mediated RNAi gene therapy against HIV-AIDS in the humanized mouse model
por: Centlivre, Mireille, et al.
Publicado: (2011)

A novel approach for inhibition of HIV-1 by RNA interference: counteracting viral escape with a second generation of siRNAs
por: ter Brake, Olivier, et al.
Publicado: (2005)

Toxicity in mice expressing short hairpin RNAs gives new insight into RNAi
por: Snøve, Ola, et al.
Publicado: (2006)

Characterization of microRNAs derived from the HIV-1 TAR RNA hairpin
por: Harwig, Alex, et al.
Publicado: (2013)

Preclinical In Vivo Evaluation of the Safety of a Multi-shRNA-based Gene Therapy Against HIV-1
por: Centlivre, Mireille, et al.
Publicado: (2013)

Endogenous spacing enables co-processing of microRNAs and efficient combinatorial RNAi
por: Amen, Alexandra M., et al.
Publicado: (2022)

Foliar Infiltration of Virus-Derived Small Hairpin RNAs Triggers the RNAi Mechanism against the Cucumber Mosaic Virus
por: Villegas-Estrada, Bernardo, et al.
Publicado: (2022)

Combinatorial delivery of small interfering RNAs reduces RNAi efficacy by selective incorporation into RISC
por: Castanotto, Daniela, et al.
Publicado: (2007)

Efficacy Analysis of Combinatorial siRNAs against HIV Derived from One Double Hairpin RNA Precursor
por: Liu, Chang, et al.
Publicado: (2017)

The interplay between virus infection and the cellular RNA interference machinery
por: Berkhout, Ben, et al.
Publicado: (2006)

Nucleic Acids-Based Therapeutics in the Battle Against Pathogenic Viruses
por: Haasnoot, Joost, et al.
Publicado: (2009)

Destabilization of the TAR hairpin leads to extension of the polyA hairpin and inhibition of HIV-1 polyadenylation
por: Vrolijk, Martine M, et al.
Publicado: (2009)

High-Throughput Construction of Intron-Containing Hairpin RNA Vectors for RNAi in Plants
por: Yan, Pu, et al.
Publicado: (2012)

Chemical induction of hairpin RNAi molecules to silence vital genes in plant roots
por: Liu, Siming, et al.
Publicado: (2016)

The virion-associated incoming HIV-1 RNA genome is not targeted by RNA interference
por: Westerhout, Ellen M, et al.
Publicado: (2006)

Combinatorial Pattern Discovery Approach for the Folding Trajectory Analysis of a β-Hairpin
por: Parida, Laxmi, et al.
Publicado: (2005)

On the role of four small hairpins in the HIV-1 RNA genome
por: Knoepfel, Stefanie A., et al.
Publicado: (2013)

RNA interference against viruses: strike and counterstrike
por: Haasnoot, Joost, et al.
Publicado: (2007)

Inhibition of Henipavirus infection by RNA interference
por: Mungall, Bruce A., et al.
Publicado: (2008)

Extracting quantitative genetic interaction phenotypes from matrix combinatorial RNAi
por: Axelsson, Elin, et al.
Publicado: (2011)

A comparison of multiple shRNA expression methods for combinatorial RNAi
por: Mcintyre, Glen J, et al.
Publicado: (2011)

Combinatorial RNAi: A Winning Strategy for the Race Against Evolving Targets?
por: Grimm, Dirk, et al.
Publicado: (2007)

Towards Antiviral shRNAs Based on the AgoshRNA Design
por: Liu, Ying Poi, et al.
Publicado: (2015)

RNAi Codex: a portal/database for short-hairpin RNA (shRNA) gene-silencing constructs
por: Olson, A., et al.
Publicado: (2006)

Design of RNAi Hairpins for Mutation-Specific Silencing of Ataxin-7 and Correction of a SCA7 Phenotype
por: Scholefield, Janine, et al.
Publicado: (2009)

MicroRNAs that interfere with RNAi
por: Massirer, Katlin B., et al.
Publicado: (2013)

Hairpin-induced tRNA-mediated (HITME) recombination in HIV-1
por: Konstantinova, Pavlina, et al.
Publicado: (2006)

Quantitative evaluation of first, second, and third generation hairpin systems reveals the limit of mammalian vector-based RNAi
por: Watanabe, Colin, et al.
Publicado: (2016)

TALEN/CRISPR-mediated engineering of a promoterless anti-viral RNAi hairpin into an endogenous miRNA locus
por: Senís, Elena, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_0a1cdsl2b99qug7sfoa4cic8qo