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DNA zip codes control an ancient mechanism for gene targeting to the nuclear periphery

Many genes are recruited to the nuclear periphery upon transcriptional activation in Saccharomyces cerevisiae. We have identified two Gene Recruitment Sequences (GRS I and II) from the promoter of the INO1 gene that target the gene to the nuclear periphery. These GRSs function as DNA zip codes; they...

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Detalles Bibliográficos
Autores principales: Ahmed, Sara, Brickner, Donna G., Light, William H., Cajigas, Ivelisse, McDonough, Michele, Froyshteter, Alexander B., Volpe, Tom, Brickner, Jason H.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835469/
https://www.ncbi.nlm.nih.gov/pubmed/20098417
http://dx.doi.org/10.1038/ncb2011