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DNA zip codes control an ancient mechanism for gene targeting to the nuclear periphery
Many genes are recruited to the nuclear periphery upon transcriptional activation in Saccharomyces cerevisiae. We have identified two Gene Recruitment Sequences (GRS I and II) from the promoter of the INO1 gene that target the gene to the nuclear periphery. These GRSs function as DNA zip codes; they...
Autores principales: | Ahmed, Sara, Brickner, Donna G., Light, William H., Cajigas, Ivelisse, McDonough, Michele, Froyshteter, Alexander B., Volpe, Tom, Brickner, Jason H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835469/ https://www.ncbi.nlm.nih.gov/pubmed/20098417 http://dx.doi.org/10.1038/ncb2011 |
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