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Biophysical and enzymatic properties of the simian and prototype foamy virus reverse transcriptases

BACKGROUND: The foamy virus Pol protein is translated independently from Gag using a separate mRNA. Thus, in contrast to orthoretroviruses no Gag-Pol precursor protein is synthesized. Only the integrase domain is cleaved off from Pol resulting in a mature reverse transcriptase harboring the protease...

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Detalles Bibliográficos
Autores principales: Hartl, Maximilian J, Mayr, Florian, Rethwilm, Axel, Wöhrl, Birgitta M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835651/
https://www.ncbi.nlm.nih.gov/pubmed/20113504
http://dx.doi.org/10.1186/1742-4690-7-5