Effects of nilotinib on regulatory T cells: the dose matters

BACKGROUND: Nilotinib is a tyrosine kinase inhibitor with high target specificity. Here, we characterized the effects of nilotinib for the first time on CD4(+)CD25(+ )regulatory T cells (Tregs) which regulate anti-tumor/leukemia immune responses. DESIGN AND METHODS: Carboxyfluorescein diacetate succ...

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Detalles Bibliográficos
Autores principales: Fei, Fei, Yu, Yingzhe, Schmitt, Anita, Rojewski, Markus T, Chen, Baoan, Greiner, Jochen, Götz, Marlies, Bunjes, Donald, Schmitt, Michael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835656/
https://www.ncbi.nlm.nih.gov/pubmed/20113470
http://dx.doi.org/10.1186/1476-4598-9-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835656/
https://www.ncbi.nlm.nih.gov/pubmed/20113470
http://dx.doi.org/10.1186/1476-4598-9-22

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