Dosage Sensitivity Shapes the Evolution of Copy-Number Varied Regions

Dosage sensitivity is an important evolutionary force which impacts on gene dispensability and duplicability. The newly available data on human copy-number variation (CNV) allow an analysis of the most recent and ongoing evolution. Provided that heterozygous gene deletions and duplications actually...

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Detalles Bibliográficos
Autores principales: Schuster-Böckler, Benjamin, Conrad, Donald, Bateman, Alex
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835737/
https://www.ncbi.nlm.nih.gov/pubmed/20224824
http://dx.doi.org/10.1371/journal.pone.0009474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835737/
https://www.ncbi.nlm.nih.gov/pubmed/20224824
http://dx.doi.org/10.1371/journal.pone.0009474

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