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Dosage Sensitivity Shapes the Evolution of Copy-Number Varied Regions

Dosage sensitivity is an important evolutionary force which impacts on gene dispensability and duplicability. The newly available data on human copy-number variation (CNV) allow an analysis of the most recent and ongoing evolution. Provided that heterozygous gene deletions and duplications actually...

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Detalles Bibliográficos
Autores principales:	Schuster-Böckler, Benjamin, Conrad, Donald, Bateman, Alex
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835737/ https://www.ncbi.nlm.nih.gov/pubmed/20224824 http://dx.doi.org/10.1371/journal.pone.0009474

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