Unique Biological Properties of Catalytic Domain Directed Human Anti-CAIX Antibodies Discovered through Phage-Display Technology

Carbonic anhydrase IX (CAIX, gene G250/MN-encoded transmembrane protein) is highly expressed in various human epithelial tumors such as renal clear cell carcinoma (RCC), but absent from the corresponding normal tissues. Besides the CA signal transduction activity, CAIX may serve as a biomarker in ea...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Chen, Lo, Agnes, Yammanuru, Anuradha, Tallarico, Aimee St. Clair, Brady, Kristen, Murakami, Akikazu, Barteneva, Natasha, Zhu, Quan, Marasco, Wayne A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835754/
https://www.ncbi.nlm.nih.gov/pubmed/20224781
http://dx.doi.org/10.1371/journal.pone.0009625

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835754/
https://www.ncbi.nlm.nih.gov/pubmed/20224781
http://dx.doi.org/10.1371/journal.pone.0009625

Ejemplares similares