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Characterization of the Activation of Protein Tyrosine Phosphatase, Receptor-Type, Z Polypeptide 1 (PTPRZ1) by Hypoxia Inducible Factor-2 Alpha

BACKGROUND: Hypoxia inducible factors (HIFs) are the principal means by which cells upregulate genes in response to hypoxia and certain other stresses. There are two major HIFs, HIF-1 and HIF-2. We previously found that certain genes are preferentially activated by HIF-2. One was protein tyrosine ph...

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Detalles Bibliográficos
Autores principales: Wang, Victoria, Davis, David A., Veeranna, Ravindra P., Haque, Muzammel, Yarchoan, Robert
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835759/
https://www.ncbi.nlm.nih.gov/pubmed/20224786
http://dx.doi.org/10.1371/journal.pone.0009641