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Discovery of Novel MicroRNAs in Female Reproductive Tract Using Next Generation Sequencing

MicroRNAs (miRNAs) are small non-coding RNAs that mediate post-transcriptional gene silencing. Over 700 human miRNAs have currently been identified, many of which are mutated or de-regulated in diseases. Here we report the identification of novel miRNAs through deep sequencing the small RNAome (<...

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Detalles Bibliográficos
Autores principales: Creighton, Chad J., Benham, Ashley L., Zhu, Huifeng, Khan, Mahjabeen F., Reid, Jeffrey G., Nagaraja, Ankur K., Fountain, Michael D., Dziadek, Olivia, Han, Derek, Ma, Lang, Kim, Jong, Hawkins, Shannon M., Anderson, Matthew L., Matzuk, Martin M., Gunaratne, Preethi H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835764/
https://www.ncbi.nlm.nih.gov/pubmed/20224791
http://dx.doi.org/10.1371/journal.pone.0009637