Clinical physiology and mechanism of dizocilpine (MK-801): Electron transfer, radicals, redox metabolites and bioactivity

Dizocilpine (MK-801), an extensively investigated drug possessing secondary amine and benzenoid functions, displays a wide array of biological properties, including anticonvulsant and anesthetic. There is scant discussion of biomechanism. A relevant, important finding is formation of oxidative metab...

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Detalles Bibliográficos
Autores principales: Kovacic, Peter, Somanathan, Ratnasamy
Formato: Texto
Lenguaje:English
Publicado: Landes Bioscience 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835885/
https://www.ncbi.nlm.nih.gov/pubmed/20716924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835885/
https://www.ncbi.nlm.nih.gov/pubmed/20716924

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