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The fat-1 transgene in mice increases antioxidant potential, reduces pro-inflammatory cytokine levels, and enhances PPARγ and SIRT-1 expression on a calorie restricted diet

Both n-3 fatty acids (FA) and calorie-restriction (CR) are known to exert anti-inflammatory and anti-oxidative effects in animals and humans. In this study, we investigated the synergistic anti-inflammatory and anti-oxidative capacity of n-3 FA and CR using Fat-1 transgenic mice (Fat-1) that are cap...

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Detalles Bibliográficos
Autores principales: Rahman, Md Mizanur, Halade, Ganesh V, Bhattacharya, Arunabh, Fernandes, Gabriel
Formato: Texto
Lenguaje:English
Publicado: Landes Bioscience 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835919/
https://www.ncbi.nlm.nih.gov/pubmed/20716918