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Kinetochore alignment within the metaphase plate is regulated by centromere stiffness and microtubule depolymerases

During mitosis in most eukaryotic cells, chromosomes align and form a metaphase plate halfway between the spindle poles, about which they exhibit oscillatory movement. These movements are accompanied by changes in the distance between sister kinetochores, commonly referred to as breathing. We develo...

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Detalles Bibliográficos
Autores principales: Jaqaman, Khuloud, King, Emma M., Amaro, Ana C., Winter, Jennifer R., Dorn, Jonas F., Elliott, Hunter L., Mchedlishvili, Nunu, McClelland, Sarah E., Porter, Iain M., Posch, Markus, Toso, Alberto, Danuser, Gaudenz, McAinsh, Andrew D., Meraldi, Patrick, Swedlow, Jason R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835940/
https://www.ncbi.nlm.nih.gov/pubmed/20212316
http://dx.doi.org/10.1083/jcb.200909005