Vaccinia Virus F1L Interacts with Bak Using Highly Divergent Bcl-2 Homology Domains and Replaces the Function of Mcl-1

The Bcl-2 family regulates induction of apoptosis at the mitochondria. Essential to this regulation are the interactions between Bcl-2 family members, which are mediated by Bcl-2 homology (BH) domains. Vaccinia virus F1L is a unique inhibitor of apoptosis that lacks significant sequence similarity w...

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Detalles Bibliográficos
Autores principales: Campbell, Stephanie, Hazes, Bart, Kvansakul, Marc, Colman, Peter, Barry, Michele
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836074/
https://www.ncbi.nlm.nih.gov/pubmed/19955184
http://dx.doi.org/10.1074/jbc.M109.053769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836074/
https://www.ncbi.nlm.nih.gov/pubmed/19955184
http://dx.doi.org/10.1074/jbc.M109.053769

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