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Analysis of a β-helical region in the p55 domain of Helicobacter pylori vacuolating toxin

BACKGROUND: Helicobacter pylori is a gram-negative bacterium that colonizes the human stomach and contributes to the development of gastric cancer and peptic ulcer disease. VacA, a toxin secreted by H. pylori, is comprised of two domains, designated p33 and p55. Analysis of the crystal structure of...

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Detalles Bibliográficos
Autores principales: Ivie, Susan E, McClain, Mark S, Algood, Holly M Scott, Lacy, D Borden, Cover, Timothy L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836311/
https://www.ncbi.nlm.nih.gov/pubmed/20178613
http://dx.doi.org/10.1186/1471-2180-10-60