A dual function TAR Decoy serves as an anti-HIV siRNA delivery vehicle

The TAR RNA of HIV was engineered as an siRNA delivery vehicle to develop a combinatorial therapeutic approach. The TAR backbone was found to be a versatile backbone for expressing siRNAs. Upon expression in human cells, pronounced and specific inhibition of reporter gene expression was observed wit...

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Detalles Bibliográficos
Autores principales: Unwalla, Hoshang J, Rossi, John J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836314/
https://www.ncbi.nlm.nih.gov/pubmed/20144240
http://dx.doi.org/10.1186/1743-422X-7-33

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836314/
https://www.ncbi.nlm.nih.gov/pubmed/20144240
http://dx.doi.org/10.1186/1743-422X-7-33

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