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Selective Elimination of a Chemoresistant Side-Population of B-CLL Cells by Cytotoxic T Lymphocytes in Subjects Receiving an Autologous hCD40L/IL-2 Tumor Vaccine

Side-population (SP) analysis identifies precursor cells in normal and malignant tissues. Cells with this phenotype have increased resistance to many cytotoxic agents, and in malignant disease may represent a primary drug resistant population. To discover whether drug resistant malignant SP cells ar...

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Detalles Bibliográficos
Autores principales: Foster, Aaron E, Okur, Fatma V, Biagi, Ettore, Lu, An, Dotti, Gianpietro, Yvon, Eric, Savoldo, Barbara, Carrum, George, Goodell, Margaret A, Heslop, Helen E, Brenner, Malcolm K
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836398/
https://www.ncbi.nlm.nih.gov/pubmed/20072155
http://dx.doi.org/10.1038/leu.2009.281