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Chimeric tRNAs as tools to induce proteome damage and identify components of stress responses

Misfolded proteins are caused by genomic mutations, aberrant splicing events, translation errors or environmental factors. The accumulation of misfolded proteins is a phenomenon connected to several human disorders, and is managed by stress responses specific to the cellular compartments being affec...

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Detalles Bibliográficos
Autores principales: Geslain, Renaud, Cubells, Laia, Bori-Sanz, Teresa, Álvarez-Medina, Roberto, Rossell, David, Martí, Elisa, de Pouplana, Lluís Ribas
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836549/
https://www.ncbi.nlm.nih.gov/pubmed/20007146
http://dx.doi.org/10.1093/nar/gkp1083