Frame-disrupting mutations elicit pre-mRNA accumulation independently of frame disruption

The T-cell receptor (TCR) and immunoglobulin (Ig) genes are unique among vertebrate genes in that they undergo programmed rearrangement, a process that allows them to generate an enormous array of receptors with different antigen specificities. While crucial for immune function, this rearrangement m...

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Detalles Bibliográficos
Autores principales: Imam, J. Saadi, Gudikote, Jayanthi P., Chan, Wai-kin, Wilkinson, Miles F.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836556/
https://www.ncbi.nlm.nih.gov/pubmed/20007599
http://dx.doi.org/10.1093/nar/gkp1115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836556/
https://www.ncbi.nlm.nih.gov/pubmed/20007599
http://dx.doi.org/10.1093/nar/gkp1115

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