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Frame-disrupting mutations elicit pre-mRNA accumulation independently of frame disruption
The T-cell receptor (TCR) and immunoglobulin (Ig) genes are unique among vertebrate genes in that they undergo programmed rearrangement, a process that allows them to generate an enormous array of receptors with different antigen specificities. While crucial for immune function, this rearrangement m...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836556/ https://www.ncbi.nlm.nih.gov/pubmed/20007599 http://dx.doi.org/10.1093/nar/gkp1115 |