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In vitro selection of oligonucleotides that bind double-stranded DNA in the presence of triplex-stabilizing agents

A SELEX approach has been developed in order to select oligonucleotides that bind double-stranded DNA in the presence of a triplex-stabilizing agent, and was applied to a target sequence containing an oligopurine–oligopyrimidine stretch. After only seven rounds of selection, the process led to the i...

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Detalles Bibliográficos
Autores principales: Ayel, Elodie, Escudé, Christophe
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836567/
https://www.ncbi.nlm.nih.gov/pubmed/20007154
http://dx.doi.org/10.1093/nar/gkp1139