The N-terminus of Prp1 (Prp6/U5-102 K) is essential for spliceosome activation in vivo

The spliceosomal protein Prp1 (Prp6/U5-102 K) is necessary for the integrity of pre-catalytic spliceosomal complexes. We have identified a novel regulatory function for Prp1. Expression of mutations in the N-terminus of Prp1 leads to the accumulation of pre-catalytic spliceosomal complexes containin...

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Detalles Bibliográficos
Autores principales: Lützelberger, Martin, Bottner, Claudia A., Schwelnus, Wiebke, Zock-Emmenthal, Susanne, Razanau, Aleh, Käufer, Norbert F.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836577/
https://www.ncbi.nlm.nih.gov/pubmed/20007600
http://dx.doi.org/10.1093/nar/gkp1155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836577/
https://www.ncbi.nlm.nih.gov/pubmed/20007600
http://dx.doi.org/10.1093/nar/gkp1155

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