Inhibition of gut-derived serotonin synthesis: a potential bone anabolic treatment

Osteoporosis is a low bone mass disease most often caused by an increase in bone resorption not compensated by a similar hike in bone formation1. Since gut–derived serotonin (GDS) inhibits bone formation2, we asked whether hampering its biosynthesis could treat osteoporosis through an anabolic mecha...

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Detalles Bibliográficos
Autores principales: Yadav, Vijay K., Balaji, Santhanam, Suresh, P.S., Liu, X. Sherry, Lu, Xin, Li, Zhishan, Guo, X. Edward, Mann, J. John, Balapure, Anil K., Gershon, Michael D., Medhamurthy, R., Vidal, Marc, Karsenty, Gerard, Ducy, Patricia
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836724/
https://www.ncbi.nlm.nih.gov/pubmed/20139991
http://dx.doi.org/10.1038/nm.2098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836724/
https://www.ncbi.nlm.nih.gov/pubmed/20139991
http://dx.doi.org/10.1038/nm.2098

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