The Endoplasmic Reticulum–associated Degradation of the Epithelial Sodium Channel Requires a Unique Complement of Molecular Chaperones

The epithelial sodium channel (ENaC) is composed of a single copy of an α-, β-, and γ-subunit and plays an essential role in water and salt balance. Because ENaC assembles inefficiently after its insertion into the ER, a substantial percentage of each subunit is targeted for ER-associated degradatio...

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Detalles Bibliográficos
Autores principales: Buck, Teresa M., Kolb, Alexander R., Boyd, Cary R., Kleyman, Thomas R., Brodsky, Jeffrey L.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836957/
https://www.ncbi.nlm.nih.gov/pubmed/20110346
http://dx.doi.org/10.1091/mbc.E09-11-0944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836957/
https://www.ncbi.nlm.nih.gov/pubmed/20110346
http://dx.doi.org/10.1091/mbc.E09-11-0944

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