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Compartmentalized Cyclic Adenosine 3′,5′-Monophosphate at the Plasma Membrane Clusters PDE3A and Cystic Fibrosis Transmembrane Conductance Regulator into Microdomains

Formation of multiple-protein macromolecular complexes at specialized subcellular microdomains increases the specificity and efficiency of signaling in cells. In this study, we demonstrate that phosphodiesterase type 3A (PDE3A) physically and functionally interacts with cystic fibrosis transmembrane...

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Detalles Bibliográficos
Autores principales: Penmatsa, Himabindu, Zhang, Weiqiang, Yarlagadda, Sunitha, Li, Chunying, Conoley, Veronica G., Yue, Junming, Bahouth, Suleiman W., Buddington, Randal K., Zhang, Guangping, Nelson, Deborah J., Sonecha, Monal D., Manganiello, Vincent, Wine, Jeffrey J., Naren, Anjaparavanda P.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836961/
https://www.ncbi.nlm.nih.gov/pubmed/20089840
http://dx.doi.org/10.1091/mbc.E09-08-0655