Protein Phosphatase 2A Reactivates FOXO3a through a Dynamic Interplay with 14-3-3 and AKT

Forkhead box transcription factor FOXO3a, a key regulator of cell survival, is regulated by reversible phosphorylation and subcellular localization. Although the kinases regulating FOXO3a activity have been characterized, the role of protein phosphatases (PP) in the control of FOXO3a subcellular loc...

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Detalles Bibliográficos
Autores principales: Singh, Amrik, Ye, Min, Bucur, Octavian, Zhu, Shudong, Tanya Santos, Maria, Rabinovitz, Isaac, Wei, Wenyi, Gao, Daming, Hahn, William C., Khosravi-Far, Roya
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836964/
https://www.ncbi.nlm.nih.gov/pubmed/20110348
http://dx.doi.org/10.1091/mbc.E09-09-0795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836964/
https://www.ncbi.nlm.nih.gov/pubmed/20110348
http://dx.doi.org/10.1091/mbc.E09-09-0795

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