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Mitochondrial Dysfunction Confers Resistance to Multiple Drugs in Caenorhabditis elegans
In a previous genetic screen for Caenorhabditis elegans mutants that survive in the presence of an antimitotic drug, hemiasterlin, we identified eight strong mutants. Two of these were found to be resistant to multiple toxins, and in one of these we identified a missense mutation in phb-2, which enc...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836976/ https://www.ncbi.nlm.nih.gov/pubmed/20089839 http://dx.doi.org/10.1091/mbc.E09-08-0673 |