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Detection of distant evolutionary relationships between protein families using theory of sequence profile-profile comparison
BACKGROUND: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represented as sequence profiles is arguably the most effective homology detection strategy. However, finding the best way to repr...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837030/ https://www.ncbi.nlm.nih.gov/pubmed/20158924 http://dx.doi.org/10.1186/1471-2105-11-89 |