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Detection of distant evolutionary relationships between protein families using theory of sequence profile-profile comparison

BACKGROUND: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represented as sequence profiles is arguably the most effective homology detection strategy. However, finding the best way to repr...

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Detalles Bibliográficos
Autores principales: Margelevičius, Mindaugas, Venclovas, Česlovas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837030/
https://www.ncbi.nlm.nih.gov/pubmed/20158924
http://dx.doi.org/10.1186/1471-2105-11-89