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Animal HECT ubiquitin ligases: evolution and functional implications
BACKGROUND: HECT ubiquitin ligases (HECT E3s) are key components of the eukaryotic ubiquitin-proteasome system and are involved in the genesis of several human diseases. In this study, I analyze the patterns of diversification of HECT E3s since animals emerged in order to provide the right framework...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837046/ https://www.ncbi.nlm.nih.gov/pubmed/20175895 http://dx.doi.org/10.1186/1471-2148-10-56 |