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Animal HECT ubiquitin ligases: evolution and functional implications

BACKGROUND: HECT ubiquitin ligases (HECT E3s) are key components of the eukaryotic ubiquitin-proteasome system and are involved in the genesis of several human diseases. In this study, I analyze the patterns of diversification of HECT E3s since animals emerged in order to provide the right framework...

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Detalles Bibliográficos
Autor principal: Marín, Ignacio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837046/
https://www.ncbi.nlm.nih.gov/pubmed/20175895
http://dx.doi.org/10.1186/1471-2148-10-56