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Missense Mutations in Cancer Predisposing Genes: Can We Make Sense of Them?
In the analysis of genes associated with predispositions to malignancy the causative status of mutations can be made relatively easily where it is obvious that there is a clear disruption in the coding sequence of the gene. Difficulties arise, however, if missense mutations are identified, as these...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837294/ https://www.ncbi.nlm.nih.gov/pubmed/20223037 http://dx.doi.org/10.1186/1897-4287-3-3-123 |