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Microenvironment Modulates Osteogenic Cell Lineage Commitment in Differentiated Embryonic Stem Cells

BACKGROUND: Due to their self-renewal, embryonic stem cells (ESCs) are attractive cells for applications in regenerative medicine and tissue engineering. Although ESC differentiation has been used as a platform for generating bone in vitro and in vivo, the results have been unsatisfactory at best. I...

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Detalles Bibliográficos
Autores principales: Yamashita, Akihiro, Nishikawa, Sandi, Rancourt, Derrick E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837348/
https://www.ncbi.nlm.nih.gov/pubmed/20300192
http://dx.doi.org/10.1371/journal.pone.0009663